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CiMaas receives a LIOF grant to optimize feeder cells preparation facilitating expansion of Natural Killer cells 

CiMaas’ leading product to fight cancer is Natural Killer (NK) cells. These cells kill tumor cells directly as has been observed in pre-clinical studies, as well as in clinical studies (patients with myeloid leukemia). To obtain a large number of these NK cells to treat patients, so-called feeder cells are needed to stimulate the proliferation and activation of NK cells.

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CiMaas to present at Biotech Showcase 2023

CiMaas BV, a biotechnology company developing the next generation of immuno-oncology therapeutics based on its proprietary NK cell expansion platform, announced the date for a presentation of the company at the Biotech Showcase 2023, the investor conference as follows: Monday, January 09, 2023, at 3:00PM at the Hilton San Francisco - Union Square, 333 O'Farrell Street, Ballroom Level San Francisco, CA 94102, USA.

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CiMaas reaches next milestone in NK cell expansion and function

CiMaas successfully expands Natural Killer (NK) cells to clinically relevant numbers using a 2-week protocol. Starting from 200 ml peripheral blood, NK are expanded to numbers meeting the expected clinically required 10.E8 cells/kg, with multiple infusions. This makes the expansion method developed directly applicable for clinical application of the produced NK cells in anti-cancer therapies. 

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CiMaas and Kiadis decided to stop collaborating on the production of Natural Killer Cells

While CiMaas is able to produce the required high numbers of natural killer (NK) cells intended to realise in the collaboration, we decided not to continue. Kiadis has refocused its clinical strategy to a concept of universal donors while CiMaas keeps working on the process of individual donors for each cancer patient where NK cells will be transfused in combination with a bone marrow transplantation.  

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CiMaas and the INsTRuCT Consortium receive EU subsidy to train young scientists in developing novel cell therapies

Cell therapy is an active area of immunological research and represents a highly innovative and rapidly expanding sector of the pharmaceutical industry. CiMaas is part of the the INsTRuCT Consortium (www.instruct-h2020.eu) which comprises 15 different European companies or universities from 8 Member States, that answers an unmet need for postdoctoral researchers trained in scientifically excellent research and cell therapy development.

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Neuroplast and CiMaas join forces

Neuroplast and CiMaas, developers and producers of regenerative cell therapies, are setting up joint shop at the Brightlands Chemelot Campus in Geleen where they will be sharing a new laboratory and office space. Both companies currently employ around 30 people and expect to experience substantial growth.

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CiMaas featured in Brightlands media campaign

The national campaign - to the end of June 2019 - airs radiospots and runs advertisements in several national newspapers to draw attention to the collaboration between the University and Brightlands in developing solutions for important societal issues. CiMaas regenerates the immune system to fight cancer.

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CiMaas obtains gene therapy classification from EMA for its’ DC vaccine

Upon a recent application and discussion with EMA, Cimaas received the classification for its' dendritic cell vaccine. EMA/CAT considers that the WT1-DC-Xcite-L1 falls within the definitions of a somatic cell therapy medicinal product and a gene therapy medicinal product and based on that is considered as gene therapy medicinal product as provided in Article 2(5) of Regulation (EC) No 1394/2007.